Rohit Sharma is named among the Impact Subs. Mumbai will want their former captain to bounce back to form, while SRH will be hoping that Abhishek Sharma continues his rampaging batting form from the last match.
MI's big hopes rest on Bumrah against the power-packed SRH batting line-up, featuring big-hitters like Abhishek, Travis Head, Ishan Kishan and Heinrich Klaasen.
It will be an emotional game for Kishan, who plays against MI at the Wankhede -- whom he played for seven seasons before he was released last year.
Check out the playing XIs of the two teams:
Mumbai Indians: Hardik Pandya (captain), Ryan Rickelton (w/k), Will Jacks, Suryakumar Yadav, Tilak Varma, Naman Dhir, Mitchell Santner, Deepak Chahar, Trent Boult, Jasprit Bumrah, Karn Sharma.
Impact Subs: Rohit Sharma, Corbin Bosch, Ashwani Kumar, Raj Bawa, Robin Minz.
Sunrisers Hyderabad: Pat Cummins (captain), Travis Head, Abhishek Sharma, Heinrich Klaasen (w/k), Ishan Kishan, Nitish Kumar Reddy, Aniket Verma, Harshal Patel, Zeeshan Ansari, Mohammed Shami, Eshan Malinga.
Impact Subs: Abhinav Manohar, Jaydev Unadkat, Sachin Baby, Rahul Chahar, Wiaan Mulder