The American, who tested positive for the stimulant modafinil at last year's world championships and is still waiting for the U.S. Anti-Doping Agency to consider her case, faded badly during the 200 metres to finish sixth.
LaTasha Colander-Richardson, of the U.S., won in 22.50 seconds with compatriot Chryste Gaines, who was given a public warning after a positive test for modafinil last year, second in 23.28.
The U.S. also dominated the men's 100 metres with Shawn Crawford clocking a wind-assisted 9.86 seconds to lead a clean sweep for the country.
Justin Gatlin was second (9.95) and Marcus Brunson (9.96) third as the first five finishers all broke 10 seconds thanks to the 2.6 metres per second tail wind. The maximum wind permitted is two metres per second.
Three-times world and Olympic javelin champion Jan Zelezny finished fourth with a best throw of 77.46 metres over four metres down on German winner Boris Henry (82.06).
Algeria's Djabir Said Guerni also failed to live up to expectations as the world champion finished fourth in the men's 800 metres behind Kenyan Justus Koech, who ran the fastest time in the world this year 1:45.37.
Wilfred Bungei (1:45.47) and Joseph Mutua (1:46.31)
World 5,000 metres champion Eliud Kipchoge brushed aside Qatar's Saif Saaeed Shaheen to win the 3,000 in a world leading time of 7:33.37.
Kenyan-born Shaheen, who won the world 3,000 metres steeplechase title for Qatar last year, finished over a second behind his former team mate in 7.34.67.
India's Anju Bobby George won the women's long jump with a wind-aided effort 6.82 metres on her final attempt.
George, who became India's first world championship medallist when she won bronze in Paris, had fouled her first two jumps which looked to be over seven metres.
