Results: Men's singles | Women's singles
Defending champion Justine Henin-Hardenne was dumped out of the French Open at the second-round stage on Wednesday when she was beaten 7-5, 6-4 by Italian Tathiana Garbin, ranked 86th in the world.
The top-seeded Belgian, who has won three of the past four Grand Slam events, was completely out of sorts and slumped to defeat in one hour, 58 minutes.
The result made Henin-Hardenne the first top seed to lose before the third round in the 79-year history of the women's singles.
Her defeat was also the earliest by a defending champion in the event since Arantxa Sanchez Vicario lost at the same stage in 1990.
In another upset, Spain's Alex Corretja bounced Thai 13th seed Paradorn Srichaphan out with a 6-4, 7-5, 6-3 victory in the second round.
Despite his seeding, Paradorn had been unfancied against the 30-year-old Corretja, runner-up at the French Open in 1998 and 2001.
Corretja, a former world number two, next faces Argentine 22nd seed Juan Ignacio Chela in the third round.
Former French Open champion Carlos Moya took just 78 minutes to clinch a bittersweet victory over fellow Spaniard and best friend Fernando Vicente.
The 27-year-old won 6-1, 6-2, 6-1 for his 11th straight win over Vicente to stroll into the French Open third round.
"Well, it's not easy. He's my best friend on the tour, and I know he's having a hard time now because he was injured for a long time," Moya said.
"Now he's trying to recover, and he's trying to be at the same level as he was before. But still he is not playing that well. That's not easy, because I am also playing very solid... with a lot of confidence. So you know, it was not easy."
Having lost all 10 previous matches against Moya, Vicente appeared to merely go through the motions on Court Suzanne Lenglen and never looked like denting the baseliner's game.
Moya, champion in Paris in 1998, is seeded fifth this time round and faces either Dutchman Raemon Sluiter or Slovak Dominik Hrbaty next.
France's Amelie Mauresmo had to fight back against Spaniard Anabel Medina Garrigues before qualifying for the third round with a 6-0, 4-6, 6-1 win.
The third seed, one of the favourites after back to back victories in Berlin and Rome in the last month, seemed in complete control in the first set before faltering in the second.
Medina Garrigues raised her level of play, forcing Mauresmo into long rallies and led 3-1 in the second set before winning it 6-4.
Mauresmo was fortunate to regain the upper hand in a one-sided third set as Medina Garrigues received treatment in the third game for a left thigh problem.
The Frenchwoman, who won in one hour and 56 minutes, meets another Spanish player, Arantxa Parra Santonja, in the third round.
Britain's Tim Henman marched through to the third round with a 6-0, 6-3, 6-3 demolition of German Lars Burgsmueller.
The 29-year-old ninth seed matched his best performance at Roland Garros with a superb display on court one and showed no sign of the tiredness he had complained of after his five-set, first round win over Cyril Saulnier.
Henman wrapped up the first set in only 20 minutes with a near-flawless display of shotmaking and Burgsmueller, ranked 91, was never in contention after that.
Henman, who could face second seed Andy Roddick in the quarter-finals, plays Spanish clay specialist Galo Blanco in the third round.
Results:
Men's singles matches on Wednesday (prefix number denotes seeding):
Second round: Julien Jeanpierre (France) beat 27-Vincent Spadea (U.S.) 6-4, 6-2, 7-5; 11-Nicolas Massu (Chile) beat Vladimir Voltchkov (Belarus) 6-3, 6-1, 6-0; Raemon Sluiter (Netherlands) beat 31-Dominik Hrbaty (Slovakia) 6-4, 6-4, 3-6, 7-6 (7-5); Mario Ancic (Croatia) beat 30-Mariano Zabaleta (Argentina) 6-3, 6-4, 3-6, 6-4; 9-Tim Henman (Britain) beat Lars Burgsmueller (Germany) 6-0, 6-3, 6-3; Galo Blanco (Spain) beat Luis Horna (Peru) 2-6, 6-4, 1-6, 6-2, 6-3; Nicolas Escude (France) beat Florian Mayer (Germany) 6-4, 6-3, 6-4; 5-Carlos Moya (Spain) beat Fernando Vicente (Spain) 6-1, 6-2, 6-1; Alex Corretja (Spain) beat 13-Paradorn Srichaphan (Thailand) 6-4, 7-5, 6-3; 3-Guillermo Coria (Argentina) beat Juan Monaco (Argentina) 7-5, 6-1, 6-3; 22-Juan Ignacio Chela (Argentina) beat Fernando Verdasco (Spain) 7-5, 6-2, 6-2.
First round: Gaston Gaudio (Argentina) beat Guillermo Canas (Argentina) 6-2, 2-6, 4-6, 6-3, 6-2.
Women's singles:
Second round: 14-Paola Suarez (Argentina) beat Vera Douchevina (Russia) 6-1, 6-4; Tathiana Garbin (Italy) beat 1-Justine Henin-Hardenne (Belgium) 7-5, 6-4; 3-Amelie Mauresmo (France) beat Anabel Medina Garrigues (Spain) 6-0, 4-6, 6-1; Tatiana Perebiynis (Ukraine) beat Ashley Harkleroad (U.S.) 6-1, 6-3; Marlene Weingartner (Germany) beat Maria Elena Camerin (Italy) 4-6, 6-4, 6-4; 9-Elena Dementieva (Russia) beat Nicole Pratt (Australia) 6-2, 6-2, 19-Anna Smashnova-Pistolesi (Israel) beat Klara Koukalova (Czech Republic) 6-1, 7-5; 18-Maria Sharapova (Russia) beat Rita Grande (Italy) 6-2, 6-0; 10-Vera Zvonareva (Russia) beat Magui Serna (Spain) 5-7, 6-1, 6-4; Arantxa Parra Santonja (Spain) beat 28-Lisa Raymond (U.S.) 6-4, 6-0; Jie Zheng (China) beat 31-Emilie Loit (France) 6-4, 6-1; 8-Nadia Petrova (Russia) beat Yuliana Fedak (Ukraine) 6-0, 6-1.
