According to the study, volume loss to the deep cheek fat compartment results in 'hollowing' of the face.
It further noted that volume loss of the deep cheek fat compartment could be the determining factor in much of what a person observes as aging in the midface.
Researchers found that when the volume was restored deep within the cheek, using fat, tissue fillers or an implant, improvement in the hollowing of the face became apparent immediately.
The study noted that finally, when the injection was done correctly into the fat compartment, a smaller volume of fat or filler was needed.
Photograph: Timm Schamberger/AFP/Getty Images
Also see: Footwear in every colour of the rainbow