Following is the list of ministers and their portfolios:
| M Karunanidhi |
Home General Administration Indian Administrative Police services and Police Industries, Information Technology Mines and Minerals Prohibition Excise Minority welfare Tamil official language Tamil Culture |
| K Anbazhagan |
Finance Legislature Elections |
| Arcot N Veersamy |
Electricity Non-conventional energy Rural and small industries |
| M K Stalin |
Municipal administration Rural Development Panchayats, Panchayat unions Poverty alleviation programmes Urban and rural water supply |
| Ko Si Mani |
Co-operatives Statistics |
| Veerapandi S Arumugham |
Agriculture Agri-engineering Sugarcane Agri co-operatives Horticulture |
| Duraimurugan |
Public works Minor irrigation |
| P T R Palanivelrajan |
Hindu Religious Charitable endowments |
| K Ponmudi |
Higher Education Electronics Science and Technology |
| K N Nehru | Transport |
| M R K Pannerselvam |
Bacward classes Registration |
| I Periyasamy |
Revenue Law |
| Sureshrajan | Tourism |
| Paruthi Ilamvazhuthy |
Information Stationary andprinting Urban development Chennai Metropolitan Development |
| A V Velu | Food and Civil Supplies |
| Suba Thangavelan | Housing |
| K K S S R Ramachandran |
Health Medical education |
| Thangam Tenarassu | School Education |
| S N M Upayathulla | Commercial Taxes |
| T P M Mohideen Khan |
Pollution Control Sports Youth welfare Wakf |
| N Selvaraj | Forests |
| P Saminathan |
Highways Ports |
| Dr Poongothai | Social Welfare |
| Geetha Jeevan | Animal Husbandry |
| Tamizharasi | Adi dravidar welfare |
| K P P Sami | Fisheries |
| U Mathivanan | Dairy Development |
| Tamizharasi | Adi dravidar welfare |
| K Ramachandran | Khadi |
