Australia vice-captain Ricky Ponting, who made a century in each of the first three Tests against the West Indies, was left out of the team for the fourth and final match on Friday because of a viral infection.
Ponting has spent five days in bed suffering from flu-like symptoms, including high temperature and sore throat, and his place will be taken by Martin Love, who makes his third Test appearance and his first of the series.
The West Indies made two changes to the team which lost the third Test by nine wickets.
Wicketkeeper Ridley Jacobs returned on his home ground after missing the last two matches with a torn groin muscle, replacing Carlton Baugh, while Jamaican fast bowler Mervyn Dillon was recalled after being dropped in Barbados.
Dillon came in for Tino Best, who had a torrid time on his debut in Bridgetown.
Australia captain Steve Waugh won the toss and chose to bat on a dry, bare pitch which, like the previous three in Georgetown, Port of Spain and Bridgetown, is expected to favour the batsmen.
Australia lead the series 3-0.
