Opener Gary Kirsten became the third member of South Africa's World Cup squad to step down from international one-day cricket on Sunday.
Kirsten, 35, joins Allan Donald and Jonty Rhodes in retirement from the squad who failed to get past the first round. He will continue to be considered for Test cricket.
All-rounder Lance Klusener has been rested from international cricket and was not included in a 14-man squad named on Sunday to play in Sharjah and Bangladesh this month.
New captain Graeme Smith, who replaces the sacked Shaun Pollock, will lead a side containing five players who were not selected for the World Cup.
The other players in the World Cup 15 to be omitted are Nicky Boje, Charl Langeveldt and Monde Zondeki.
Fast bowler Zondeki was involved in a car accident on Saturday and is expected to be out of action for a month with an injured left shoulder.
The new members of the South Africa squad are Paul Adams, Allan Dawson, Neil McKenzie, Jacques Rudolph and Charl Willoughby.
The team: Graeme Smith (captain), Paul Adams, Mark Boucher, Allan Dawson, Boeta Dippenaar, Herschelle Gibbs, Andrew Hall, Jacques Kallis, Neil McKenzie, Makhaya Ntini, Robin Peterson, Shaun Pollock, Jacques Rudolph, Charl Willoughby.