The 173rd-ranked Indian lost 6-2, 1-6, 4-6 to the 164th-ranked Jurgen Zopp of Estonia.
World No. 168 Saketh Myneni is the last Indian standing, having edged out compatriot and Chennai Open quarter-finalist Ramkumar Ramanathan 6-4, 6-1.
Myneni will next face 261st-ranked Italian Lorenzo Giustino on Friday for a place in the final round of qualifying at the year’s first Grand Slam.
- Sania-Martina win 29th consecutive match, break 22-year-old record
Image: Somdev Devvarman
Chennai Open: Wawrinka breezes into quarters; Indians advance
Sania maintains top spot, Bopanna ninth in doubles rankings
Chennai Open: Wild carder Ramkumar marches on but Somdev knocked out
Somdev rallies to qualify for Chennai Open main draw
Ramkumar wins hearts in defeat, Wawrinka in semis