However, Prakash Amritraj's campaign ended with a loss in the second round.
Fourth-seeded Somdev came back from a set down to beat the Slovak 3-6, 6-3, 6-4 in the second round of the hardcourt event.
Prakash, however, went down by a tame 1-6, 3-6 margin against second seed and Davis Cupper Yen-Hsun Lu.
Somdev, who is out of the doubles event after losing in the first round, next faces Czech Republic's Dusan Lojda.
Prakash's challenge is over in doubles event as well, after he and partner Marin ko Matosevic lost the opening round 4-6, 4-6 against the top seeded Thai pair of Sanchai and Sonchat Ratiwatana.
Another Indian who tasted defeat was Purav Raja, who along with Australian partner Sadik Kadir, lost his first round match 7-5, 2-6, 8-10 to the Japanese pair of Hiroki Kondo and GO Soeda.
Tashkent Challenger: Bopanna in round II
Somdev, Mankad advance in US Challenger
LA: Somdev loses in singles
Somdev enters Vancouver quarters
Somdev, Prakash advance in Seoul ATP Challenger