Soderling had defeated Rafael Nadal before losing to Roger Federer in the final of the French Open this year.
Marin Cilic, the winner of the previous edition, has already confirmed his participation.
"Chennai Open is a much awaited event in the international tennis circuit. India is a fascinating country and I am looking forward to visiting India and playing at the tournament this year," Soderling said in a statement.
M A Alagappan, President of the Tamil Nadu Tennis Association, said, "Tennis fans in Chennai and India will be excited with this confirmation from Robin Soderling. He is one of the top ranked players in the world and his presence will enthrall the players and fans alike. We are delighted to host him at Aircel Chennai Open 2010."
The Chennai Open commences on January 4 and concludes on January 10.