Second seed Sanam beat Canadia’s Braydenx Schnur 7-5, 6-1 while fourth seed Vijayant got the better of eighth seed Fritz Wolmarans of South Africa 7-6(3), 6-2.
In the semi-finals, Malik will meet top seed Peter Polansky while Sanam will take on fifth seed Michael Shabaz of the United States.
In the Sharm-al-Sheikh event in Egypt, Arjun Kadhe lost 5-7, 4-6 to Colombian wild card and eighth seed C Rodrigues in the second round, leaving N Sriram Balaji as the only Indian in the draw.
Balaji faces local qualifier Mazen Osama in the quarter-finals.
In doubles, though, Kadhe had some success as he reached the semi-finals with Spanish partner Pol Toledo Bague.
They beat the Indo-Morocco combo of Sasi Kumar Mukund and Mohamed Adnaoui 6-2, 6-2.
Up next for them are local fourth seeds Karim Hossam and K Maamoun.
Balaji and his Indian partner Ranjeet Murali Murugesan also reached the semis after beating Skander Mansouri and Marlon Oliveira 6-3, 6-2.
They will meet the Syrian pair of Marc Abdelnour and Issam Haitham Taweel.
Image: Sanam Singh