Saha started his career at Metz before spells at Newcastle United, Fulham, Manchester United, Everton, Tottenham Hotspur, Sunderland and Italian club Lazio last season.
"Want to thank all managers, all staff, all team mates, all opponents, all fans, for all support and love towards me during my football career," Saha said on Twitter.
"I'm a proud man but without you all I won't be myself now. Thanks for the challenges, thanks for the help, thanks for the memories, thanks for the passion.
"I will stop to be call(ed) a professional footballer. Love you and thanks again."
Image: Louis Saha
Photograph: Gabriele Maltinti/Getty Images
Fabregas dismisses Barcelona exit talk
Spurs deserve to be in the Champions League: Soldado
Manchester City's Nastasic to miss start of season
EPL: Mystery over Bale's Madrid transfer saga continues
Sunday special: Wigan fly flag for second tier in curtain-raiser