Indian ace Leander Paes and his Zimbabwean partner Cara Black suffered a straight-set defeat to Anna-Lena Groenefeld and Mark Knowles and bowed out of the mixed doubles at the US Open in New York on Tuesday.
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The second seeds, who won the 2010 Wimbledon mixed doubles title, lost 3-6, 4-6 to the German-Bahamian pair in the quarter-finals.
Paes and Black had clinched the Australian Open mixed doubles title in January.
India's Rohan Bopanna and his Pakistani partner Aisam-ul-Haq Qureshi are still in the reckoning in the men's doubles. They take on the South African-Belgian combo of Wesley Moodie and Dick Norman in the quarter-final.
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