The 34-year-old, who is a five-time world champion besides being an Olympic bronze-medallist, beat local favourite Diem Thi Trinh Kieu in a split verdict in the opening round of the light flyweight (48kg) category.
The four-time gold-medallist is making a return to her preferred weight division after competing in the 51kg category, which was made an Olympic category before the 2012 Games.
It was a sedate start to the proceedings as Mary Kom and her rival spent the better part of the first three minutes getting a measure of each other.
The pace picked up in the second round and the Indian veteran was on top with her clean straights. Mary Kom's reflexes were sharp and she kept maintaining the right distance to deny Kieu a clear shot at her.
The local favourite, backed by a partisan crowd, gave a better account of herself in the final three minutes but Mary Kom also stepped it up with some telling combination blows to throw Kieu off-balance.
Mary Kom will next take on Chinese Taipei's Meng- Chieh Ping, who got the better of Thailand's Panpradab Plodsai in her opening bout.
A total of 107 boxers from 20 countries are competing in the continental meet where India are placed third in the all-time medals' list with 19 gold, 21 silver and 20 bronze.
File Image: MC Mary Kom celebrates winning her bout.
Photograph: Chung Sung-Jun/Getty Images
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