Italy midfielder Claudio Marchisio will miss this year's European Championship after tearing knee ligaments during Juventus' 4-0 Serie A victory over Palermo on Sunday.
The 30-year-old midfielder will undergo surgery this week.
"Claudio is a great person and a true champ," his Juventus and Italy team mate Leonardo Bonucci said on Twitter.
"It's a big loss."
Marchisio's injury marred a good weekend for Juventus, who moved nine points clear at the top of the table after thrashing Palermo.
Image: Juventus' Claudio Marchisio
Photograph: Giorgio Perottino