Italy midfielder Claudio Marchisio will miss this year's European Championship after tearing knee ligaments during Juventus' 4-0 Serie A victory over Palermo on Sunday.
The 30-year-old midfielder will undergo surgery this week.
"Claudio is a great person and a true champ," his Juventus and Italy team mate Leonardo Bonucci said on Twitter.
"It's a big loss."
Marchisio's injury marred a good weekend for Juventus, who moved nine points clear at the top of the table after thrashing Palermo.
Image: Juventus' Claudio Marchisio
Photograph: Giorgio Perottino
Dipa Karmakar creates history, first Indian gymnast to qualify for Olympics
Bundesliga: Teenager Pulisic puts Dortmund close on heels of Bayern
Gayle's no show not a worry for RCB captain Kohli, here's why...
La Liga PHOTOS: Barca lose to Valencia while Atletico catch up
Serie A: Juventus restore lead with Atalanta win