Arsenal joined Manchester United and Liverpool on the FA Cup scrapheap on Sunday when Ricardo Fuller's double helped Stoke City to a 3-1 fourth round victory at the Britannia Stadium.
Fuller's opening goal in the second minute was trademark Stoke, the striker getting on the end of Rory Delap's huge throw-in.
Arsenal, who included the returning Sol Campbell, equalised shortly before halftime with a deflected strike from Denilson but Fuller restored Stoke's lead with 13 minutes remaining, wrong-footing Lucasz Fabianski with a close-range header after a superb run and cross by Mamady Sidibe.
Dean Whitehead made sure of Stoke's first FA Cup victory against Arsenal from Matthew Etherington's low cross.
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