India's challenge in the men's doubles event of the US Open ended with the defeat of Rohan Bopanna and his Australian partner Matthew Ebden in the third round, in New York.

The second seeded Bopanna-Ebden pair lost 1-6, 5-7 to the 16th seed Argentine combo of Maximo Gonzalez and Andres Molteni in 66 minutes on Sunday.

Bopanna and Ebden had won the Australian Open early this year.

The 44-year-old Bopanna has already announced retirement from Davis Cup and it will be interesting to see if he will return to defend his Australian Open crown in January 2025.

Sumit Nagal had exited the men's singles with an opening round defeat while Yuki Bhambri and N Sriram Balaji earlier lost in men's doubles at different stages of the tournament.

Bopanna's challenge is still alive in the mixed doubles event with Indonesian partner Aldila Sutjiadi and interestingly, he and Ebden will now be up against each other.

Ebden and Czech Republic's Barbora Krejcikova are seeded fourth in the mixed doubles.

India's Yuki Bhambri and his French partner Albano Olivetti exited the US Open with a straight-set loss to top seeds Marcel Granollers and Horacia Zeballos in the men's doubles round of 16.

The top-seeded Spanish-Argentine pair defeated the Indo-French combine 6-2, 6-2.

Bhambri and Olivetti did well to reach the pre-quarterfinals, having got the better of 15th seeds Austin Krajicek and Jean-Julien Roger in the second round.

Earlier, Bopanna and his Indonesian partner Aldila Sutjiadi progressed to the mixed doubles quarter-finals after losing the first set without getting a single game, turning it around remarkably at the US Open.