In the best traditions of celebrity weddings, the location has been kept secret, although several newspapers report the pair will tie the knot amidst the neo-Gothic splendour of Highclere Castle in Berkshire, where glamour model Jordan and singer Peter Andre married last year.
A glittering cast from the worlds of football and showbiz is expected.
Arsenal defender Cole, 25, rumoured to be on his way to Chelsea, was generally judged to have had a good World Cup, as did Tweedy, 23.
The singer with pop group Girls Aloud was one of the most prominent of the WAGs (Wives And Girlfriends), whose prodigious shopping and night-life exploits received almost as many column inches in the papers as their footballing partners did for their on-pitch performances.
The celebrations on Saturday will give both Cole and Tweedy the opportunity to put a line under recent controversies.
Cole was fined last year by the Premier League for making contact with Chelsea without telling Arsenal and Tweedy was found guilty in 2003 of assault after an altercation in a Guildford nightclub. She was fined and ordered to do community service.