Six MLAs each from Anantapuram and Guntur districts, three from Krishna district and one from Kadapa district tendered their resignations, party sources said.
Payyavula Keshav, MLA from Anantapuram district, told PTI over phone that "we have faxed our resignations to the speaker's office".
TDP sources said the resignations were in protest against the Centre's "failure" to come out with a firm assurance on development of Andhra-Rayalaseema regions upon bifurcation.
"The Centre also did not give any commitment on protecting the interests of farmers and youth," they added.
Sources said more MLAs of the party were expected to quit from the House tomorrow in the backdrop of growing protests in Andhra-Rayalaseema against the move to bifurcate AP.
Image: Telangana supporters protest in Hyderabad
Photograph: SnapsIndia