The long-suffering actor was in Pennsylvania for medical treatment.
The body of Mehmood, who died in his sleep, will be brought to Mumbai to his brother Usman Ali.
Mehmood worked in more than 300 films in a career spanning almost three decades. His memorable films include Gumnaam, Bhoot Bangla, Padosan, Pyar Kiye Ja, Kunwara Baap, and Bombay To Goa.
As a director, his last film was Dushman Duniya Ka in 1996. The film, which introduced his son Manzoor Ali, had special appearances from Shah Rukh Khan and Salman Khan. His second son of eight children, Maqsood 'Lucky' Ali is a well-known Hindi pop singer.
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