The Nifty declined 72 points, at 4,943 and the Sensex lost 244 points, at 16,453.
The Nifty opened lower tracking subdued global cues as concerns over how the European bailout fund would help the Greece and other countries from averting a default took the front seat.
The Nifty reversed losses and touched a high of 5,025 in the mid morning session.
However, the index was unable to sustain the recovery and it slipped again to end near the day's low, tracking losses across European bourses.
The Sensex and Nifty were up almost 2% for the week, but posted their biggest quarterly fall in three years, down 12% in the September quarter.
Markets across Asia also posted a quarterly loss.
The Nikkei Stock Average closed flat, at 8,695 and the China's Shanghai Composite slipped 0.3% and Hong Kong's Hang Seng plunged 2.3% as they played catch up after the holiday.
The Nikkei index was down over 11%, while the Hang Seng index plunged over 21% in the September quarter.
In Europe, the FTSE 100, CAC 40 and the DAX plummeted almost 2% each as the Euro-zone debt concerns continued to loom on the investor sentiment.
Back in India, the Central Bureau of Investigations statement on the 2G scam weighed on Anil Dhirubhai Ambani group stocks -- Reliance Communication fell 8%, Reliance Capital declined 13% and Reliance Infrastructure slipped 7%.
Mining shares were also among the worst hit after the cabinet approved the new mining bill which calls for miners to share maximum 26%
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