Matrix Partners, which has raised $1.1 billion in two tranches currently has investments in 27 firms, of which 10 have an offshore presence in India.
"Many of Matrix Partners portfolio companies have either a presence in India for their R&D work or have Indian founders," Matrix General Partner Tim Barrows said.
The 14 year-old Matrix has invested in Veritas, Tivoli Systems, Apollo Computer, Cascade Communications and Sycamore Networks.