South Africa called up the uncapped Johan Botha as part of a three-pronged spin attack for the five-match one-day international tour of India starting next week.
The 23-year-old took up off-spin bowling just two years ago, having entered first-class cricket for Eastern Province as a medium-pacer.
Slow left-armer Robin Peterson, who has taken just nine wickets in 21 one-day internationals, and Justin Ontong, who bowls off and leg-breaks but has taken just eight wickets in 18 matches, are the other spinners in the 15-man squad announced on Sunday.
The inclusion of a third spinner has cost top-order batsman Jacques Rudolph his place in the squad, with Ontong also a talented limited-overs batsman and speedy fielder.
The South Africans will play a warm-up match in Hyderabad on November 14 before playing five one-day internationals between November 16 and 28.
Squad: Graeme Smith (captain), AB de Villiers, Jacques Kallis, Ashwell Prince, Justin Kemp, Justin Ontong, Mark Boucher, Shaun Pollock, Albie Morkel, Andrew Hall, Robin Peterson, Johan Botha, Charl Langeveldt, Makhaya Ntini, Andre Nel.